4-Morpholineethanesulfonic acid
Application- Product Name
- 4-Morpholineethanesulfonic acid
- CAS No.
- 4432-31-9
- Chemical Name
- 4-Morpholineethanesulfonic acid
- Synonyms
- MES;2-(N-MORPHOLINO)ETHANESULFONIC ACID;2-MORPHOLINOETHANESULFONIC ACID;MES 2-Morpholinoethanesulfonic acid;ME1;TIMTEC-BB;2-(N-Morpholino)ethanesulfonic;4-MORPHOLINOETHANESULFONIC ACID;MKS1;BBS13
- CBNumber
- CB3100297
- Molecular Formula
- C6H13NO4S
- Formula Weight
- 195.24
- MOL File
- 4432-31-9.mol
4-Morpholineethanesulfonic acid Property
- Melting point:
- >300 °C(lit.)
- Boiling point:
- 102°C
- Density
- 1.208 (estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- 2-8°C
- solubility
- H2O: 0.5 M at 20 °C, clear
- form
- Powder
- pka
- pKa at 0.1M ionic: 0°, 6.38; 20°, 6.15; 37°, 5.98; pKa1 1.99; pKa2 6.21; pKa/°C -0.011
- color
- White
- PH
- 2.5-4.0 (25℃ in neat)
- PH Range
- 5.5 - 6.7
- Water Solubility
- 185.2g/L at 20℃
- λmax
- λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01 - Merck
- 13,5929
- BRN
- 6350956
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChIKey
- SXGZJKUKBWWHRA-UHFFFAOYSA-N
- LogP
- -2.2 at 20℃
- CAS DataBase Reference
- 4432-31-9(CAS DataBase Reference)
- EPA Substance Registry System
- 4-Morpholineethanesulfonic acid (4432-31-9)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25-22
- WGK Germany
- 1
- RTECS
- QE9104530
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 76039
- Product name
- MES solution
- Purity
- BioUltra, for molecular biology, 0.5?M in H2O
- Packaging
- 100ML
- Price
- $206
- Updated
- 2024/03/01
- Product number
- 475893
- Product name
- MES, Free Acid, ULTROL® Grade
- Purity
- A zwitterionic buffer useful in the pH range of 5.5-6.5. Has a pKa of 6.10 at 25°C. Absorbance (1.0 M, H2O, 260 nm):0.05.
- Packaging
- 100G
- Price
- $115
- Updated
- 2024/03/01
- Product number
- 76039
- Product name
- MES solution
- Purity
- BioUltra, for molecular biology, 0.5?M in H2O
- Packaging
- 500ML
- Price
- $818
- Updated
- 2024/03/01
- Product number
- 475893
- Product name
- MES, Free Acid, ULTROL® Grade
- Purity
- A zwitterionic buffer useful in the pH range of 5.5-6.5. Has a pKa of 6.10 at 25°C. Absorbance (1.0 M, H2O, 260 nm):0.05.
- Packaging
- 500G
- Price
- $561
- Updated
- 2024/03/01
- Product number
- 475893
- Product name
- MES, Free Acid, ULTROL® Grade
- Purity
- A zwitterionic buffer useful in the pH range of 5.5-6.5. Has a pKa of 6.10 at 25°C. Absorbance (1.0 M, H2O, 260 nm):0.05.
- Packaging
- 1KG
- Price
- $787
- Updated
- 2024/03/01
4-Morpholineethanesulfonic acid Chemical Properties,Usage,Production
Application
4-Morpholineethanesulfonic acid (MES) is one of the good′s buffers, and the most extensively application is biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring and it does not form complexes with the majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes. MES has been also used as a component of the elution buffer used to elute plasma from α2-macroglobulin affinity column. It has been used as an activation buffer during antibody conjugation to microparticles and it has been used in the functionalization of microchannels during the creation of microfluidic-integrated surface plasmon resonance (SPR) platform for pathogen detection.
Chemical Properties
White/clear crystalline powder
Uses
MES solution has been used to activate microspheres. It has also been used as a component of activating solution to activate carboxyl groups of poly lactic-co-glycolic acid (PLGA).
Uses
Biological buffer.
Definition
ChEBI: 2-(N-morpholino)ethanesulfonic acid is a Good's buffer substance, pKa = 6.15 at 20 ℃. It is an organosulfonic acid and a MES. It is a conjugate acid of a 2-(N-morpholino)ethanesulfonate. It is a tautomer of a 2-(N-morpholiniumyl)ethanesulfonate.
General Description
MES is one of the Good′s buffers, the most extensively used biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring. It does not form complexes with majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes.
Flammability and Explosibility
Not classified
storage
Store at RT
Purification Methods
Crystallise MES from hot EtOH containing a little water. The picrate crystallises from EtOH and has m 178.8-182o. [Malkiel & Mason J Org Chem 8 199 1943, Beilstein 27 III/IV 370.]
4-Morpholineethanesulfonic acid Preparation Products And Raw materials
Raw materials
Preparation Products
4-Morpholineethanesulfonic acid Suppliers
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View Lastest Price from 4-Morpholineethanesulfonic acid manufacturers
- Product
- 4-Morpholineethanesulfonic acid 4432-31-9
- Price
- US $8.00-2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-24
- Product
- 4-Morpholineethanesulfonic acid 4432-31-9
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20mt/mon
- Release date
- 2023-09-05
- Product
- 4-Morpholineethanesulfonic acid 4432-31-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 3500kg/month
- Release date
- 2021-09-09